This possibility is suggested by the fact that arthritis is the hallmark of CAE. In this article, we shall consider an additional aspect of CAE, namely the possibility of using this disease as a model for arthritis in humans. Moreover, the economic losses caused by CAE have become more obvious and CAE eradication programs have been established in several countries. CAE, along with other lentiviral infections of domestic animals, shares some of the features of AIDS, such as a long and variable incubation time and lifelong persistence, but differs by not causing immunodeficiency. CAE virus, also referred to as caprine lentivirus, is a member of the same subfamily as the viruses causing AIDS, the human immunodeficiency viruses (HIV). Interest in this disease has increased in recent years mainly for two reasons. doi:10.Caprine arthritis-encephalitis (CAE) is a disease in goats which occurs worldwide. Control of caprine arthritis-encephalitis virus infection in three Norwegian goat herds. Efecto del virus de artritis encefalitis caprina en el aparato reproductor de machos caprinos effect of the caprine arthritis encephalitis virus in the reproductive system of male goats. Systemic and in vitro expression of goat α1-acid glycoprotein during Caprine Arthritis-Encephalitis Virus infection. doi:10.1016/j.vetmic.2005.01.012Ĭeciliani F, Rahman MM, Lecchi C, Maccalli M, Pisoni G, Sartorelli P. Diagnostic tests for small ruminant lentiviruses. Caprine arthritis-encephalitis syndrome (CAE): a review. Further investigations need to be done to explore the seroconversion of CAEV in small ruminants and the associated factors to plan an appropriate eradication program and prevent transmission.Ĭaprine arthritis encephalitis goats seroprevalence.Īl-Ani FK, Vestweber JGE. This disease poses serious animal health problems that constrain production with the presence of apparent clinical signs. This finding indicates that CAEV infection exists in the goat flocks in examined localities in Ethiopia. There has been a significant difference ( p 0.05) of goats. ![]() ![]() The overall seroprevalence of CAE was 4.7%. Of the total samples tested from clinical cases, 7 (58.3%) were sero-positive for the presence of antibodies against CAEV. Chronic pneumonia was the highest cause of goat morbidity (50.8%) and mortality (100.0%). ![]() Records have been statistically analyzed by using the chi-square test.ĭuring five consecutive years of longitudinal clinical study, a total of 195 clinical diseases of chronic pneumonia, nerve problems, clinical mastitis, and arthritis occurred with prevalence of 99 (50.8%), 57 (29.2%), 27 (13.9%), and 12 (6.2%), respectively. A total of 257 serum samples have been collected from apparently health and clinical cases attributed to CAE infection and tested with the usage of indirect enzyme-linked immunosorbent assays to screen antibodies against CAE. The present study was conducted to determine the rate of morbidity and mortality due to clinical diseases attributed to infection by Caprine arthritis encephalitis virus (CAEV) and to determine the serological status of CAEV in goat in North Shewa, Ethiopia.Ī cross-sectional serological study and a longitudinal clinical case study were conducted. ![]() It is mainly manifested as encephalitis in kids and polyarthritis in adult goats. Caprine arthritis encephalitis (CAE) is a chronic debilitating and economically important viral disease of goats.
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